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The Oncologist
Article . 2023 . Peer-reviewed
License: CC BY
Data sources: Crossref
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The Oncologist
Article . 2023
Data sources: Europe PubMed Central
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PubMed Central
Other literature type . 2023
License: http://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
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Claim

KRAS: Druggable at Last

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 18 Mar 2023 English Publisher:Oxford University Press (OUP)Journal:The Oncologist, volume 28, pages 283-286 (issn: 1083-7159, eissn: 1549-490X, Copyright policy )
Authors: Benjamin O Herzberg; Gulam A Manji;

doi: 10.1093/oncolo/oyad014

pmid: 36933199

pmc: PMC10078900

KRAS: Druggable at Last

Abstract

The approval of adagrasib for non–small cell lung cancer is a milestone in drug development. This commentary highlights the history of the research that led to this breakthrough that will help many patients with KRAS-mutated cancers to live longer and better.

Related Organizations
Keywords

Proto-Oncogene Proteins p21(ras), Lung Neoplasms, Commentaries, Mutation, Humans, Signal Transduction

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 11
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Top 10%
Average
Top 10%
Green
gold
Related to Research communities
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Cancer Research