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Systematic Screening for Tuberculosis Using Molecular Testing on Stool Samples in Acutely Malnourished Children: A Pilot Implementation Study in a High-Burden Drug-Resistant Tuberculosis Country

Authors: Joan Martínez-Campreciós; Juan Espinosa-Pereiro; Arlete Nindia; Maria Cerezuela; Marta Sales; Ermelinda Tchiloka; Elena Trigo; +7 Authors

Systematic Screening for Tuberculosis Using Molecular Testing on Stool Samples in Acutely Malnourished Children: A Pilot Implementation Study in a High-Burden Drug-Resistant Tuberculosis Country

Abstract

Abstract Systematic screening of tuberculosis (TB) using molecular testing on stool samples detected TB in 5.2% of acutely malnourished children, including cases without evident clinical symptoms. This screening strategy could enhance TB diagnosis and facilitate prompt treatment initiation in this population. Further studies are required to confirm long-term outcomes and cost-effectiveness.

Keywords

ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Mass Screening, Infectious Diseases in Special Populations, Other subheadings::Other subheadings::Other subheadings::/drug therapy, Desnutrició, ANATOMY::Fluids and Secretions::Feces, Tuberculosi - Tractament, NAMED GROUPS::Persons::Age Groups::Child, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, Excrements, Tuberculosi - Diagnòstic, DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Actinomycetales Infections::Mycobacterium Infections::Tuberculosis::Tuberculosis, Multidrug-Resistant, DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño, ENFERMEDADES::enfermedades nutricionales y metabólicas::trastornos nutricionales::desnutrición, Other subheadings::Other subheadings::/diagnosis, DISEASES::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition, DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Actinomycetales Infections::Mycobacterium Infections::Tuberculosis, Otros calificadores::Otros calificadores::/diagnóstico, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::cribado sistemático, ANATOMÍA::líquidos y secreciones::heces, Cribatge (Medicina), ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias grampositivas::infecciones por Actinomycetales::micobacteriosis::tuberculosis::tuberculosis resistente a múltiples medicamentos, Microorganismes - Resistència als medicaments, Infants, ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias grampositivas::infecciones por Actinomycetales::micobacteriosis::tuberculosis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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Average
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