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Nucleic Acids Research
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REBASE—a database for DNA restriction and modification: enzymes, genes and genomes

Authors: Richard J Roberts; Tamas Vincze; Janos Posfai; Dana Macelis;

REBASE—a database for DNA restriction and modification: enzymes, genes and genomes

Abstract

Abstract REBASE is a comprehensive and extensively curated database of information about the components of restriction-modification (RM) systems. It is fully referenced and provides information about the recognition and cleavage sites for both restriction enzymes and DNA methyltransferases together with their commercial availability, methylation sensitivity, crystal and sequence data. All completely sequenced genomes and select shotgun sequences are analyzed for RM system components. When PacBio sequence data is available, the recognition sequences of many DNA methyltransferases (MTases) can be determined. This has led to an explosive growth in the number of well-characterized MTases in REBASE. The contents of REBASE may be browsed from the web rebase.neb.com and selected compilations can be downloaded by FTP (ftp.neb.com). Monthly updates are also available via email.

Related Organizations
Keywords

Internet, Binding Sites, Databases, Factual, Computational Biology, Information Storage and Retrieval, Articles, DNA, DNA Restriction Enzymes, Genomics, Sequence Analysis, DNA, DNA Methylation, Protein Structure, Tertiary, Substrate Specificity, Genes, Genome, Archaeal, Databases, Genetic, Database Issue, DNA Restriction-Modification Enzymes, Databases, Protein, DNA Modification Methylases, Genome, Bacterial, Software

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1K
Top 0.1%
Top 0.1%
Top 0.1%
Green
gold