The Pfam protein families database
Copyright policy )The Pfam protein families database
Pfam is a widely used database of protein families and domains. This article describes a set of major updates that we have implemented in the latest release (version 24.0). The most important change is that we now use HMMER3, the latest version of the popular profile hidden Markov model package. This software is approximately 100 times faster than HMMER2 and is more sensitive due to the routine use of the forward algorithm. The move to HMMER3 has necessitated numerous changes to Pfam that are described in detail. Pfam release 24.0 contains 11,912 families, of which a large number have been significantly updated during the past two years. Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/).
- Stockholm University Sweden
- Howard Hughes Medical Institute United States
- Wellcome Trust United Kingdom
- Wellcome Sanger Institute United Kingdom
- Janelia Research Campus United States
Internet, Sequence Homology, Amino Acid, Molecular Sequence Data, Computational Biology, Information Storage and Retrieval, Articles, Protein Structure, Tertiary, Biological sciences, Cardiovascular and Metabolic Diseases, Genome, Archaeal, TREES, TOOL, Animals, Humans, Amino Acid Sequence, Genome, Fungal, BLAST, Databases, Nucleic Acid, Databases, Protein, Sequence Alignment, Software
Internet, Sequence Homology, Amino Acid, Molecular Sequence Data, Computational Biology, Information Storage and Retrieval, Articles, Protein Structure, Tertiary, Biological sciences, Cardiovascular and Metabolic Diseases, Genome, Archaeal, TREES, TOOL, Animals, Humans, Amino Acid Sequence, Genome, Fungal, BLAST, Databases, Nucleic Acid, Databases, Protein, Sequence Alignment, Software
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