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Nucleic Acids Research
Article . 2004 . Peer-reviewed
Data sources: Crossref
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Nucleic Acids Research
Article
License: implied-oa
Data sources: UnpayWall
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DBLP
Article . 2004
Data sources: DBLP
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A web-based genotyping resource for viral sequences

Authors: Mikhail Rozanov; Uwe Plikat; Colombe Chappey; Andrey Kochergin; Tatiana A. Tatusova;

A web-based genotyping resource for viral sequences

Abstract

The Genotyping tool at the National Center for Biotechnology Information is a web-based program that identifies the genotype (or subtype) of recombinant or non-recombinant viral nucleotide sequences. It works by using BLAST to compare a query sequence to a set of reference sequences for known genotypes. Predefined reference genotypes exist for three major viral pathogens: human immunodeficiency virus 1 (HIV-1), hepatitis C virus (HCV) and hepatitis B virus (HBV). User-defined reference sequences can be used at the same time. The query sequence is broken into segments for comparison to the reference so that the mosaic organization of recombinant sequences could be revealed. The results are displayed graphically using color-coded genotypes. Therefore, the genotype(s) of any portion of the query can quickly be determined. The Genotyping tool can be found at: http://www.ncbi.nih.gov/projects/genotyping/formpage.cgi.

Keywords

Recombination, Genetic, Hepatitis B virus, Internet, Genes, Viral, Genotype, Molecular Sequence Data, Genome, Viral, Hepacivirus, Sequence Analysis, DNA, User-Computer Interface, DNA, Viral, Viruses, Computer Graphics, HIV-1, Sequence Alignment, Algorithms, Software

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    202
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
202
Top 10%
Top 1%
Top 10%
gold