
We describe a dedicated RNA motif search program and web server to identify RNA riboswitches. The Riboswitch finder analyses a given sequence using the web interface, checks specific sequence elements and secondary structure, calculates and displays the energy folding of the RNA structure and runs a number of tests including this information to determine whether high-sensitivity riboswitch motifs (or variants) according to the Bacillus subtilis type are present in the given RNA sequence. Batch-mode determination (all sequences input at once and separated by FASTA format) is also possible. The program has been implemented and is available both as local software for in-house installation and as a web server at http://www.biozentrum.uni-wuerzburg.de/bioinformatik/Riboswitch/.
Ribonucleic Acid Regulatory Sequences, Internet, RNA Sequence Analysis, Sequence Analysis, RNA, Messenger RNA, 570 Life Sciences, Regulatory Sequences, Ribonucleic Acid, 610 Medical Sciences, Medicine, Allosteric Regulation, Cardiovascular and Metabolic Diseases, Nucleic Acid Conformation, RNA, Messenger, Software
Ribonucleic Acid Regulatory Sequences, Internet, RNA Sequence Analysis, Sequence Analysis, RNA, Messenger RNA, 570 Life Sciences, Regulatory Sequences, Ribonucleic Acid, 610 Medical Sciences, Medicine, Allosteric Regulation, Cardiovascular and Metabolic Diseases, Nucleic Acid Conformation, RNA, Messenger, Software
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