
The cloned 18 S ribosomal RNA gene from Saccharomyces cerevisiae have been sequenced, using the Maxam-Gilbert procedure. From this data the complete sequence of 1789 nucleotides of the 18 S RNA was deduced. Extensive homology with many eucaryotic as well as E. coli ribosomal small subunit rRNA (S-rRNA) has been observed in the 3'-end region of the rRNA molecule. Comparison of the yeast 18 S rRNA sequences with partial sequence data, available for rRNAs of the other eucaryotes provides strong evidence that a substantial portion of the 18 S RNA sequence has been conserved in evolution.
Eukaryotic Cells, Base Sequence, Genes, RNA, Ribosomal, Animals, Chromosome Mapping, Humans, Saccharomyces cerevisiae, Cloning, Molecular, Biological Evolution
Eukaryotic Cells, Base Sequence, Genes, RNA, Ribosomal, Animals, Chromosome Mapping, Humans, Saccharomyces cerevisiae, Cloning, Molecular, Biological Evolution
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