Plant pathogenic RNAs and RNA catalysis
Copyright policy )Plant pathogenic RNAs and RNA catalysis
The rolling circle replication of small circular plant pathogenic RNAs requires a processing step to convert multimeric intermediates to monomers which are then circularized. Eleven such RNAs are known so far, two are viroids, one is viroid-like and the remainder are satellite RNAs dependent on a helper virus for replication. The processing step is RNA-catalysed in all cases, at least in vitro. All plus forms of these RNAs self-cleave via the hammerhead structure whereas only eight of the minus RNAs self-cleave, five via the hammerhead structure and three via the hairpin structure. There are about 20 other viroids where the processing mechanism has yet to be determined but they are likely candidates for a new type of self-cleavage reaction which is predicted to be conserved in all these viroids. Hepatitis delta RNA is the only circular pathogenic RNA known to self-cleave in the animal kingdom. It is feasible that more single-stranded circular pathogenic RNAs are waiting to be discovered and these could be prospective for new types of self-cleavage reactions.
- University of Adelaide Australia
Base Sequence, Ultraviolet Rays, Molecular Sequence Data, RNA, Circular, Viroids, Plant Viruses, Cross-Linking Reagents, Nucleic Acid Conformation, RNA, RNA, Viral, RNA, Catalytic, RNA Processing, Post-Transcriptional, Forecasting
Base Sequence, Ultraviolet Rays, Molecular Sequence Data, RNA, Circular, Viroids, Plant Viruses, Cross-Linking Reagents, Nucleic Acid Conformation, RNA, RNA, Viral, RNA, Catalytic, RNA Processing, Post-Transcriptional, Forecasting
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).117 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
Citations provided by BIP!Popularity provided by BIP!