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Nucleic Acids Research
Article . 1994 . Peer-reviewed
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Nucleic Acids Research
Article
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Nucleic Acids Research
Article . 1994
Data sources: Europe PubMed Central
https://dx.doi.org/10.1093/nar...
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DNA stretching on functionalized gold surfaces

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1994 English Publisher:Oxford University Press (OUP)Journal:Nucleic Acids Research, volume 22, pages 492-497 (issn: 0305-1048, eissn: 1362-4962, Copyright policy )
Authors: R M, Zimmermann; E C, Cox;

doi: 10.1093/nar/22.3.492

pmid: 8127690

pmc: PMC523609

DNA stretching on functionalized gold surfaces

Abstract

We describe a method for anchoring bacteriophage lambda DNA by one end to gold by Au-biotin-streptavidin-biotin-DNA bonds. DNA anchored to a microfabricated Au line could be aligned and stretched in flow and electric fields. The anchor was shown to resist a force of at least 11 pN, a linkage strong enough to allow DNA molecules of chromosome size to be stretched and aligned.

Related Organizations
Keywords

Microscopy, Electron, Electromagnetic Fields, Base Sequence, DNA, Viral, Molecular Sequence Data, Biotin, Gold, Bacteriophage lambda

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 85
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
85
Top 10%
Top 1%
Top 10%
gold