Poly(rA) ioinos poly(rG) poly(rC) to form a tripie helix

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1992 English Publisher:Oxford University Press (OUP)Journal:Nucleic Acids Research, volume 20, pages 315-318 (issn: 0305-1048, eissn: 1362-4962,

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Authors: M, Chastain; I, Tinoco;

doi: 10.1093/nar/20.2.315

pmid: 1741257

pmc: PMC310372

Poly(rA) ioinos poly(rG) poly(rC) to form a tripie helix

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Abstract

Poly(rA) binds poly(rG).poly(rC) to form a triple helix. Evidence for this structure includes ultraviolet absorbance mixing curves and melting curves, and circular dichroism spectroscopy. The formation of the triple helix depends on the length of the poly(rC) strand. Triple helix forms when the average length is around 100 nucleotides but does not form when the average length is about 500 nucleotides.

Related Organizations

University of California, Berkeley
United States

Keywords

Poly C, Macromolecular Substances, Spectrophotometry, Circular Dichroism, Poly G, Temperature, Nucleic Acid Conformation, Poly A

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