A moderately frequent HindIII polymorphism at the human NGFR locus (17q12 – 17q22)
Copyright policy )A moderately frequent HindIII polymorphism at the human NGFR locus (17q12 – 17q22)
The clone Lambda6 contains human NGFR sequences cloned in the vector CH28. HindIII (AAGCTT) reveals allelic bands of 13 kb and 8.3+4.7 kb with a constant band of 8.8 kb. The NGFR locus has been assigned to 17q12->17q22 with somatic cell hybrid analysis and in situ hybridization. The HindIII site polymorphism shows tight genetic linkage to HOX2 and other 17q markers. No significant deviation from Hardy-Weinberg equilibrium has been observed. No departure from Mendelian expectations in 39 offspring of segregating matings was found.
- University of Utah United States
- Cornell University United States
- York College United States
Polymorphism, Genetic, Chromosome Mapping, Humans, Receptors, Cell Surface, Deoxyribonuclease HindIII, Nerve Growth Factors, Receptors, Nerve Growth Factor, Polymorphism, Restriction Fragment Length, Chromosomes, Human, Pair 17
Polymorphism, Genetic, Chromosome Mapping, Humans, Receptors, Cell Surface, Deoxyribonuclease HindIII, Nerve Growth Factors, Receptors, Nerve Growth Factor, Polymorphism, Restriction Fragment Length, Chromosomes, Human, Pair 17
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