Abstract This chapter on perioperative care aims to describe the different evidence-based techniques involved in the preparation and management of patients around the time of surgery. The chapter has been updated to include the widely used WHO safety checklist and guidance on surgical site infections. New evidence regarding the use of mechanical bowel preparation and oral antibiotics, as well as extended thromboprophylaxis, has also been included. The benefits of minimally invasive surgery including robotic surgery are reviewed. This section of the text also covers some of the more common post-operative complications relating to colorectal surgery.