Treatment of Latent Tuberculosis Infection in Children

descriptionPublicationkeyboard_double_arrow_right Article 19 May 2013 English Publisher:Oxford University Press (OUP)Journal:Journal of the Pediatric Infectious Diseases Society, volume 2, pages 248-258 (issn: 2048-7193, eissn: 2048-7207,

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Authors: Andrea T, Cruz; Amina, Ahmed; Anna M, Mandalakas; Jeffrey R, Starke;

doi: 10.1093/jpids/pit030

pmid: 26619479

Treatment of Latent Tuberculosis Infection in Children

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Abstract

Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide). Based upon this review and our pediatric experience, we can offer recommendations for routine (isoniazid) and alternative courses of therapy.

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