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An Overdose of Risperidone

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1996Publisher:Oxford University Press (OUP)Journal:Journal of Analytical Toxicology, volume 20, pages 202-203 (issn: 0146-4760, eissn: 1945-2403,

Authors: Angela C. Springfield; Ed Bodiford;

doi: 10.1093/jat/20.3.202

pmid: 8735204

An Overdose of Risperidone

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Abstract

A fatality resulting from the suicidal ingestion of risperidone is described. The decedent had a lengthy history of mental illness but was otherwise healthy. Biological fluid samples obtained at autopsy were analyzed for risperidone by high-performance liquid chromatography. The blood concentration of risperidone was 1.8 mg/L, the urine concentration was 14.4 mg/L, and the concentration in the gastric contents was 34.6 mg/L (1.04 mg total). The 9-hydroxy-risperidone metabolite was not detected in the blood or gastric contents; however, the urine contained 17.8 mg/L of this metabolite.

Related Organizations

University of North Texas Health Science Center
United States

Keywords

Male, Isoxazoles, Middle Aged, Reference Standards, Risperidone, Gas Chromatography-Mass Spectrometry, Gastrointestinal Contents, Suicide, Fatal Outcome, Pyrimidines, Paliperidone Palmitate, Humans, Drug Overdose, Chromatography, High Pressure Liquid, Antipsychotic Agents

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	43
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average