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Hepatitis B e Antigen in the Absence of Hepatitis B Surface Antigen

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1980 English Publisher:Oxford University Press (OUP)Journal:Journal of Infectious Diseases, volume 141, pages 289-292 (issn: 0022-1899, eissn: 1537-6613,

Authors: Edward Tabor; Edward Tabor; John L. Ziegler; John L. Ziegler; Robert J. Gerety; Robert J. Gerety;

doi: 10.1093/infdis/141.3.289

pmid: 7365279

Hepatitis B e Antigen in the Absence of Hepatitis B Surface Antigen

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Abstract

Hepatitis B e antigen (HBeAg) was detected by agar gel diffusion in the serum of four Ugandan adults (three patients with tropical splenomegaly syndrome and one healthy adult) who did not have detectable hepatitis B surface antigen (HBsAg) by radioimmunoassay. Two of them had antibody to hepatitis B core antigen, and the other two had antibody to HBsAg. Detection of HBeAg by a relatively insensitive immunodiffusion test in the absence of HBsAg detectable by a sensitive radioimmunoassay suggested that production or removal of these two antigens may occur independently.

Related Organizations

National Institutes of Health
United States
National Cancer Institute
United States
National Institute of Health
Pakistan
United States Food and Drug Administration
United States

Keywords

Adult, Male, Hepatitis B virus, Hepatitis B Surface Antigens, Middle Aged, Hypersplenism, Hepatitis B Antigens, Humans, Female, Uganda, Cryoglobulins

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	27
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%