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Human Reproduction
Article
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Human Reproduction
Article . 1997 . Peer-reviewed
Data sources: Crossref
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Intracytoplasmic sperm injection (ICSI) and chromosomally abnormal spermatozoa

Authors: in 't Veld, P.A.; Broekmans, F.J.M.; de France, H.F.; Pearson, P.L.; Pieters, M.H.E.C.; van Kooij, R.J.;

Intracytoplasmic sperm injection (ICSI) and chromosomally abnormal spermatozoa

Abstract

An infertile couple was referred for intracytoplasmic sperm injection (ICSI) because of primary infertility and oligoasthenoteratozoospermia (OAT) in the male. It was observed that although the sperm cells presented with an unusual head size and multiple tails they were able to fertilize the oocytes after ICSI. Subsequent molecular cytogenetic analysis demonstrated de-novo chromosome abnormalities in virtually all sperm cells with 40% diploidy and 24% triploidy in addition to aneuploidy for the sex chromosomes.

Country
Netherlands
Related Organizations
Keywords

Adult, Chromosome Aberrations, Male, Sperm-Ovum Interactions, Econometric and Statistical Methods: General, Cytoplasm, Genotype, Microinjections, Chromosome Disorders, Fertilization in Vitro, Oligospermia, EMC MM-01-52-07, Algemeen onderzoek, Phenotype, Genetics, Humans, Female, Geneeskunde(GENK), EMC MGC-02-96-01, In Situ Hybridization, Fluorescence, Infertility, Male

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    104
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
104
Top 10%
Top 10%
Top 10%
bronze