
ABSTRACT Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro- and macro-nuclei of this organism for genetic studies.
Cell Nucleus, Phenotype, Tetrahymena pyriformis, Genetic Complementation Test, Chromosome Mapping, Drug Resistance, Microbial, Cycloheximide, Alleles, Genes, Dominant
Cell Nucleus, Phenotype, Tetrahymena pyriformis, Genetic Complementation Test, Chromosome Mapping, Drug Resistance, Microbial, Cycloheximide, Alleles, Genes, Dominant
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