
pmid: 23645500
This editorial refers to ‘Impact of right ventricular reserveonexercisecapacityandsurvivalinpatientswithpulmonaryhypertension’, by F.C. Blumberget al.doi.10.1093/eurjhf/hft0Pulmonary arterial hypertension (PAH) and chronic thrombo-embolicpulmonaryhypertension(CTEPH)arerareconditionsasso-ciatedwithapoorprognosis,forwhichtreatmentsareexpensiveand,at best, only moderately efficacious. Until the very latest stages ofdiseaseprogression,symptomsoccuralmostexclusivelywithphysic-al exertion, most probably reflecting insufficient oxygen delivery toperipheral muscles caused through limitations of right ventricular(RV) reserve relative to heightened pulmonary vascular afterload.
Male, PULMONARY ARTERIAL-HYPERTENSION, Cardiac & Cardiovascular Systems, Heart Ventricles, Hypertension, Pulmonary, EXERCISE, END-POINT, 6-MINUTE WALK DISTANCE, Humans, Familial Primary Pulmonary Hypertension, 1102 Cardiorespiratory Medicine and Haematology, Science & Technology, Exercise Tolerance, STROKE VOLUME, TRIALS, Cardiovascular System & Hematology, Cardiovascular System & Cardiology, SURVIVAL, Ventricular Function, Right, OXYGEN-UPTAKE, Female, Vascular Resistance, 3201 Cardiovascular medicine and haematology, Life Sciences & Biomedicine
Male, PULMONARY ARTERIAL-HYPERTENSION, Cardiac & Cardiovascular Systems, Heart Ventricles, Hypertension, Pulmonary, EXERCISE, END-POINT, 6-MINUTE WALK DISTANCE, Humans, Familial Primary Pulmonary Hypertension, 1102 Cardiorespiratory Medicine and Haematology, Science & Technology, Exercise Tolerance, STROKE VOLUME, TRIALS, Cardiovascular System & Hematology, Cardiovascular System & Cardiology, SURVIVAL, Ventricular Function, Right, OXYGEN-UPTAKE, Female, Vascular Resistance, 3201 Cardiovascular medicine and haematology, Life Sciences & Biomedicine
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