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European Heart Journal
Article . 2005 . Peer-reviewed
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Are tirofiban and abciximab identical in efficacy?

Authors: Fahim H. Jafary;

Are tirofiban and abciximab identical in efficacy?

Abstract

We read the paper by Mukherjee et al .1 on similar efficacy outcomes with tirofiban and ReoPro with a lot of interest and considerable reservations. The paper was hand-delivered to me by the representative of one of the drugs in the study with the proud claim that both drugs were equivalent. The authors are to be applauded in conducting a very well-designed trial with 100% follow-up in terms of mortality. The outcome reported was pre-specified, in line with modern concepts of trial execution. The authors also do well to point out a significant limitation of their study in …

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Keywords

Clinical Trials as Topic, Immunoglobulin Fab Fragments, Treatment Outcome, Tirofiban, Abciximab, Antibodies, Monoclonal, Humans, Tyrosine, Platelet Aggregation Inhibitors

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    10
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Average
Average
Top 10%
bronze