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Database: The Journal of Biological Databases and Curation
Article . 2018 . Peer-reviewed
License: CC BY
Data sources: Crossref
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PubMed Central
Article . 2018
License: CC BY
Data sources: PubMed Central
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DBLP
Article . 2020
Data sources: DBLP
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Drug Target Commons 2.0: a community platform for systematic analysis of drug–target interaction profiles

Authors: ZiaurRehman Tanoli; Zaid Alam; Markus Vähä-Koskela; Balaguru Ravikumar; Alina Malyutina; Alok Jaiswal; Jing Tang 0002; +2 Authors

Drug Target Commons 2.0: a community platform for systematic analysis of drug–target interaction profiles

Abstract

Drug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound-target interaction profiles. End users can search, upload, edit, annotate and export expert-curated bioactivity data for further analysis, using an application programmable interface, database dump or tab-delimited text download options. To guide chemical biology and drug-repurposing applications, DTC version 2.0 includes updated clinical development information for the compounds and target gene-disease associations, as well as cancer-type indications for mutant protein targets, which are critical for precision oncology developments.

Countries
Finland, Denmark
Keywords

INFORMATION, IMATINIB MESYLATE, ACUTE MYELOID-LEUKEMIA, ta3111, User-Computer Interface, RESOURCE, METASTATIC MELANOMA, Data Mining, Drug Interactions, Databases, Protein, MUTATION, ta317, ta112, Internet, THERAPEUTIC TARGET, ta111, KIT, ta3122, SORAFENIB, Biomedicine, DISCOVERY, Mutation, Original Article, Biological Assay, Algorithms, Software

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    52
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
52
Top 1%
Top 10%
Top 10%
Green
gold