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Radioimmunoassay for calcitonin.

descriptionPublicationkeyboard_double_arrow_right Article , Part of book or chapter of book 01 May 1982 English Publisher:Oxford University Press (OUP)Journal:Clinical Chemistry, volume 28, pages 1,219-1,226 (issn: 0009-9147, eissn: 1530-8561,

Authors: Hunter Heath; Glen W. Sizemore;

doi: 10.1093/clinchem/28.5.1219 , 10.1007/978-1-4612-5553-6_13

pmid: 7074931

Radioimmunoassay for calcitonin.

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Abstract

Calcitonin (CT) is one of the most recently discovered calcium-regulating hormones; the first brief allusion to its existence appeared in 1961.1 The first assays for CT were based on its hypocalcemic property upon injection into rats.2,3 Radioimmunoassays for animal calcitonins soon followed, but the availability of sensitive radioimmunoassays for human CT (hCT) awaited determination of the amino acid sequence synthesis of the hormone.4 There are now well over 20 published radioimmunoassays for human CT that vary in such basic elements as antisera, buffer constituents, incubation conditions, and tracer preparation; sensitivity and final results also vary.

Keywords

Adult, Calcitonin, Reference Values, Radioimmunoassay, Humans, Thyroid Neoplasms, Middle Aged

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	53
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%