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Claim

Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 19 Jun 2022 United States, United Kingdom, Netherlands English Publisher:Oxford University Press (OUP)Journal:Clinical Infectious Diseases, volume 76, pages e990-e994 (issn: 1058-4838, eissn: 1537-6591, Copyright policy )
Authors: Ntinginya, Nyanda Elias; Bakuli, Abhishek; Mapamba, Daniel; Sabiiti, Wilber; Kibiki, Gibson; Minja, Lilian Tina; Kuchaka, Davis; +7 Authors

doi: 10.1093/cid/ciac445

pmid: 35717643

pmc: PMC9907486

handle: https://repository.ubn.ru.nl/handle/2066/290932 , 2066/290932 , 10023/25735

Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse

Abstract

Abstract Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria growth indicator tube (MGIT) time to positivity (TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.

Countries
United States, United Kingdom, Netherlands
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Keywords

Clinical Sciences, NDAS, 610, Radboud University Medical Center, Clinical sciences, Medical and Health Sciences, Microbiology, Rare Diseases, SDG 3 - Good Health and Well-being, Clinical Research, Recurrence, Humans, Tuberculosis, Relapse, Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA) Consortium, Radboudumc 4: lnfectious Diseases and Global Health Pulmonary Diseases, MCC, relapse, Biomedical and Clinical Sciences, Brief Report, Sputum, 600, clinical trial, Biomarker, QR Microbiology, Mycobacterium tuberculosis, Biological Sciences, Bacterial Load, QR, Clinical trial, tuberclosis, Infectious Diseases, Orphan Drug, Emerging Infectious Diseases, Good Health and Well Being, biomarker, Infection

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 13
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Top 10%
Top 10%
Top 10%
Green
hybrid
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