
doi: 10.1093/bmb/ldx019
pmid: 28910989
Dystonia is a clinically heterogeneous group of hyperkinetic movement disorders. Recent advances have provided a better understanding of these conditions with significant clinical impact.Peer reviewed journals and reviews. PubMed.gov.A recent consensus classification, including the assessment of phenomenology and identification of the dystonia syndromes, has provided a helpful tool for the clinical assessment. New forms of monogenic dystonia have been recently identified.Despite recent advances in the understanding of dystonia, treatment remains symptomatic in most patients.Recent advances in genetics have provided a better understanding of the potential pathogenic mechanisms involved in dystonia. Deep brain stimulation has shown to improve focal and combined forms of dystonia and its indications are constantly expanding.Growing understanding of the disease mechanisms involved will allow the development of targeted and disease-modifying therapies in the future.
Dystonia, Consensus, Botulinum toxin, Deep Brain Stimulation, Humans, dystonia, Syndrome, Forecasting
Dystonia, Consensus, Botulinum toxin, Deep Brain Stimulation, Humans, dystonia, Syndrome, Forecasting
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