Abstract Introduction The aim of this paper is to analyze the validity and safety of a new robotic approach implantation program in the corporocaudal pancreatectomy (PCC) in a Bilio-Pancreatic Unit, evaluating morbi-mortality and hospital stay. Methods Given the controversy of which is the best therapeutic option in distal pancreatectomy in clinical process surgery tributaries, we designed this prospective, non-randomized, single-center study of pancreatic resection with Robotic approach). Ten patients (7 women and 3 men) were included, with a mean age of 57.8 years, (range 36–73 years). In all patients, the body mass index was higher than 30 and the diagnosis was made with a preoperative computed tomography. Results The robotic approach was successful in all cases, performing a corporal-caudal pancreatectomy associated with splenectomy. Blood loss was minimal during intervention, not requiring any blood transfusion. The mean operative time was 135.8 minutes. Conversion to open surgery was not necessary. Three patients had postoperative complications when a CT scan diagnosed an intra-abdominal collection in the left hypocondrium. It was resolved by percutaneous radiological drainage. Median hospital stay was 4 days (3–15). There was not perioperative mortality at 90 days. Anatomopathological study showed 5 mucinous cystic neoplasms, 2 adenocarcinomas of the pancreas and 3 well-differentiated neuroendocrine tumors. Mean size of the lesions were 4.8 cm (2.4–9). Conclusions Robotic distal pancreatectomy is an effective and safe technique. In addition, postoperative morbidity and hospital stay decreases.