
doi: 10.1093/bja/70.3.273
pmid: 8471368
We have determined the minimum alveolar concentration (MAC) for sevoflurane in elderly patients (mean age 71.4 yr). MAC was found to be 1.48 (SEM 0.08)%, which is smaller than the values for children and adults. The magnitude of the change in MAC with age is similar to that for halothane and isoflurane. The calculated anesthetic ED95 for preventing 95% of patients from moving was 1.98%.
Aged, 80 and over, Male, Methyl Ethers, Age Factors, Middle Aged, Pulmonary Alveoli, Sevoflurane, Tidal Volume, Humans, Female, Aged, Anesthetics, Ethers
Aged, 80 and over, Male, Methyl Ethers, Age Factors, Middle Aged, Pulmonary Alveoli, Sevoflurane, Tidal Volume, Humans, Female, Aged, Anesthetics, Ethers
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