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British Journal of Anaesthesia
Article
License: Elsevier Non-Commercial
Data sources: UnpayWall
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British Journal of Anaesthesia
Article . 1980 . Peer-reviewed
License: Elsevier Non-Commercial
Data sources: Crossref
British Journal of Anaesthesia
Article . 1980
Data sources: Europe PubMed Central
https://dx.doi.org/10.1093/bja...
Article
Data sources: Microsoft Academic Graph
https://dx.doi.org/10.1093/bja...
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EVALUATION OF GLYCOPYRROLATE AND ATROPINE AS ADJUNCTS TO REVERSAL OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS IN A “TRUE-TO-LIFE” SITUATION

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1980 English Publisher:Elsevier BVJournal:British Journal of Anaesthesia, volume 52, pages 85-89 (issn: 0007-0912, Copyright policy )
Authors: D A, Cozanitis; J W, Dundee; J D, Merrett; C J, Jones; R K, Mirakhur;

doi: 10.1093/bja/52.1.85

pmid: 6990948

EVALUATION OF GLYCOPYRROLATE AND ATROPINE AS ADJUNCTS TO REVERSAL OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS IN A “TRUE-TO-LIFE” SITUATION

Abstract

Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease.

Related Organizations
Keywords

Atropine, Male, Clinical Trials as Topic, Pyrrolidines, Time Factors, Neuromuscular Junction, Middle Aged, Glycopyrrolate, Neostigmine, Random Allocation, Double-Blind Method, Heart Rate, Humans, Female, Neuromuscular Blocking Agents

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 61
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
61
Average
Top 1%
Top 10%
hybrid