Abstract Summary: MiSearch is an adaptive biomedical literature search tool that ranks citations based on a statistical model for the likelihood that a user will choose to view them. Citation selections are automatically acquired during browsing and used to dynamically update a likelihood model that includes authorship, journal and PubMed indexing information. The user can optionally elect to include or exclude specific features and vary the importance of timeliness in the ranking. Availability: http://misearch.ncibi.org Contact: dstates@umich.edu Supplementary information: Supplementary data are available at Bioinformatics online.