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Bioinformatics
Article
Data sources: UnpayWall
Bioinformatics
Article . 2004 . Peer-reviewed
Data sources: Crossref
Bioinformatics
Article . 2005
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MACAT--microarray chromosome analysis tool

Authors: Matthias Heinig; Benjamin Georgi; Sebastian Schmeier; Joern Toedling; Stefan Roepcke;

MACAT--microarray chromosome analysis tool

Abstract

By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of specific chromosomes. We have implemented a statistical approach for identifying significantly differentially expressed chromosome regions. We demonstrate the applicability of the approach on a publicly available data set on acute lymphocytic leukemia.The R-package MACAT can be obtained from http://www.compdiag.molgen.mpg.de/software/macat.shtmlhttp://www.compdiag.molgen.mpg.de/software/macat.shtml.

Keywords

Models, Statistical, Gene Frequency, Models, Genetic, Gene Expression Profiling, Chromosome Mapping, Computer Simulation, Algorithms, Linkage Disequilibrium, Software, Oligonucleotide Array Sequence Analysis

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    27
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
27
Average
Top 10%
Top 10%
bronze
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