A program to optimize DNA sequences for protein expression

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1990 English Publisher:Oxford University Press (OUP)Journal:Bioinformatics, volume 6, pages 399-400 (issn: 1367-4803, eissn: 1460-2059,

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Authors: William Bains;

doi: 10.1093/bioinformatics/6.4.399

pmid: 2257502

A program to optimize DNA sequences for protein expression

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Abstract

THOYO is a program that combines sequence feature identification with automatic editing to allow the rapid optimization of «reverse translation» sequence. Data, entered as amino acid sequence in single or triple letter code, is automatically reverse translated using the most frequent codons of man, Saccharomyces cerevisiae or Escherichia coli

Related Organizations

PA Consulting Group
United Kingdom

Keywords

Base Sequence, Microcomputers, Software Design, Molecular Sequence Data, Programming Languages, Amino Acid Sequence, DNA, Software

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