Restriction site mapping is in separation theory

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1988 English Publisher:Oxford University Press (OUP)Journal:Bioinformatics, volume 4, pages 97-101 (issn: 1367-4803, eissn: 1460-2059,

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Authors: Lloyd Allison; Chut N. Yee;

doi: 10.1093/bioinformatics/4.1.97

pmid: 2838139

Restriction site mapping is in separation theory

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Abstract

A computer algorithm for restriction-site mapping consists of a generator of partial maps and a consistency checker. This paper examines consistency checking and argues that a method based on separation theory extracts the maximum amount of information from fragment lengths in digest data. It results in the minimum number of false maps being generated.

Related Organizations

Monash University
Australia

Keywords

Chromosome Mapping, DNA, DNA Restriction Enzymes, Algorithms, Software

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