DNA methylation, nucleosome formation and positioning
Copyright policy )DNA methylation, nucleosome formation and positioning
Recent mapping of nucleosome positioning on several long gene regions subject to DNA methylation has identified instances of nucleosome repositioning by this base modification. The evidence for an effect of CpG methylation on nucleosome formation and positioning in chromatin is reviewed here in the context of the complex sequence-structure requirements of DNA wrapping around the histone octamer and the role of this epigenetic mark in gene repression.
- University of Edinburgh United Kingdom
Macromolecular Substances, DNA, DNA Methylation, Chromatin, Nucleosomes, Gene Expression Regulation, Neoplastic, Histones, Neoplasms, Animals, Humans, CpG Islands, Promoter Regions, Genetic, Protein Binding
Macromolecular Substances, DNA, DNA Methylation, Chromatin, Nucleosomes, Gene Expression Regulation, Neoplastic, Histones, Neoplasms, Animals, Humans, CpG Islands, Promoter Regions, Genetic, Protein Binding
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).59 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!