Metformin-related vitamin B12 deficiency

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2006 English Publisher:Oxford University Press (OUP)Journal:Age and Ageing, volume 35, pages 200-201 (issn: 0002-0729, eissn: 1468-2834,

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Authors: Kin Wah, Liu; Lok Kwan, Dai; Woo, Jean;

doi: 10.1093/ageing/afj042

pmid: 16495296

Metformin-related vitamin B12 deficiency

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Abstract

Metformin is an invaluable hypoglycaemic agent. We report two cases who had symptomatic vitamin B12 deficiency related to metformin use; the mechanisms are discussed. The clinician must be aware of the possibility of metformin-associated B12 deficiency in users who suffer cognitive impairment, peripheral neuropathy, subacute combined degeneration of the cord or anaemia.

Related Organizations

Shatin Hospital
China (People's Republic of)
Hospital Authority
China (People's Republic of)

Keywords

Aged, 80 and over, Diarrhea, Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Female, Vitamin B 12 Deficiency, Metformin

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