
pmid: 8831877
One hundred and twenty-four patients over the age of 75 years were assessed for the cause of their macrocytosis (MCV > 95 fl). A definitive diagnosis was reached in 75/124 (60%) by non-invasive techniques. The remainder underwent a bone marrow biopsy yielding a definitive diagnosis in a further six patients who had an identifiable myelodysplastic syndrome (MDS). A high proportion of the remainder had morphological abnormalities which fitted with no recognized pathological entity. It is suggested that these may represent MDS in evolution.
Aged, 80 and over, Erythrocyte Indices, Male, Biopsy, Needle, Bone Marrow, Myelodysplastic Syndromes, Hemoglobinometry, Humans, Female, Anemia, Macrocytic, Geriatric Assessment, Aged
Aged, 80 and over, Erythrocyte Indices, Male, Biopsy, Needle, Bone Marrow, Myelodysplastic Syndromes, Hemoglobinometry, Humans, Female, Anemia, Macrocytic, Geriatric Assessment, Aged
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