
pmid: 29265955
Rotavirus is the most important cause of gastroenteritis worldwide. In developing countries, the virus is a major cause of death in infants and young children. In the United States, before the licensure of vaccines, rotavirus infections accounted for ∼2.7 million cases of gastroenteritis annually. Here are described the history and challenges surrounding the development of a rotavirus vaccine.
Rotavirus, Drug Evaluation, Preclinical, Rotavirus Vaccines, History, 20th Century, History, 21st Century, Rotavirus Infections, United States, Gastroenteritis, Disease Models, Animal, Drug Discovery, Animals, Humans
Rotavirus, Drug Evaluation, Preclinical, Rotavirus Vaccines, History, 20th Century, History, 21st Century, Rotavirus Infections, United States, Gastroenteritis, Disease Models, Animal, Drug Discovery, Animals, Humans
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 12 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
