
pmid: 16796519
Ethanolic extract from seeds of Pterodon polygalaeflorus (Benth) has been shown to possess significant larvicidal activity against the mosquito Aedes aegypti. Bioassay-guided fractionation of the extract led to the isolation and characterization of the know diterpenoid furans 6alpha-hydroxyvouacapan-7beta,17beta-lactone (1), 6alpha,7beta-dihydroxyvouacapan- 17beta-oic acid (2) and methyl 6alpha,7beta-dihydroxyvouacapan-17beta-oate (3). The structures were established from infrared (IR), ultraviolet (UV), 1H-nuclear magnetic resonance (NMR), 13C-NMR, and mass spectral data: full NMR assignments are presented for compounds 1-3 and the diacetyl derivative of 3. Compounds 1-3 exhibited LC50 values of 50.08, 14.69, and 21.76 microg/mL against fourth-instar Aedes aegypti larvae.
Insecticides, Magnetic Resonance Spectroscopy, Plant Extracts, Fabaceae, Aedes, Larva, Seeds, Animals, Biological Assay, Diterpenes, Pest Control, Biological
Insecticides, Magnetic Resonance Spectroscopy, Plant Extracts, Fabaceae, Aedes, Larva, Seeds, Animals, Biological Assay, Diterpenes, Pest Control, Biological
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