Unusual Malabsorption of Levothyroxine

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2000 English Publisher:SAGE PublicationsJournal:Thyroid, volume 10, pages 93-95 (issn: 1050-7256, eissn: 1557-9077,

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Authors: B, Jauk; P, Mikosch; H J, Gallowitsch; E, Kresnik; M, Molnar; I, Gomez; P, Lind;

doi: 10.1089/thy.2000.10.93

pmid: 10691319

Unusual Malabsorption of Levothyroxine

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Abstract

We report a 50-year-old woman, with overt hypothyroidism undergoing thyrotropin (TSH)-stimulating hormone suppressive levothyroxine (LT4) treatment after subtotal thyroidectomy. At her first visit to our department, the laboratory results revealed a borderline low free thyroxine (FT4) level accompanied by a clearly elevated TSH level. Both parameters did not significantly change during therapy with an oral dose of 500 microg of LT4. Investigations revealed malabsorption of oral administrated LT4. Thyroid serum hormone levels only became normal during parenteral therapy with LT4.

Keywords

Thyroid Gland, Administration, Oral, Thyrotropin, Middle Aged, Carcinoma, Papillary, Thyroxine, Hypothyroidism, Malabsorption Syndromes, Thyroidectomy, Humans, Triiodothyronine, Female, Infusions, Parenteral, Thyroid Neoplasms

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