Autonomy in Endemic Goiter

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1998 Belgium English Publisher:SAGE PublicationsJournal:Thyroid, volume 8, pages 107-113 (issn: 1050-7256, eissn: 1557-9077,

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Authors: Corvilain, Bernard; Van Sande, Jacqueline; Dumont, Jacques Emile; Bourdoux, Pierre; Ermans, André Marie;

doi: 10.1089/thy.1998.8.107

pmid: 9492160

handle: 2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/55739

Autonomy in Endemic Goiter

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Abstract

The occurrence of hyperthyroidism in many individuals after introduction of iodine prophylaxis in endemic goiter areas can have dramatic consequences for the affected individuals. It indicates that in such individuals the increase of serum thyroid hormone level in response to iodine supplementation does not exert its normal negative feedback on thyroid activity, ie, that in such individuals some thyroid tissue has become autonomous. In this short review we summarize what is known about the possible mechanisms, cause, diagnosis, and consequences of thyroid autonomy.

Country

Belgium

Related Organizations

Université Libre de Bruxelles
Belgium
Boston University Brussels
Belgium

Keywords

Mutation -- physiology, Endemic -- prevention & control, Goiter, Thyroid Gland, Sciences bio-médicales et agricoles, Iodine -- deficiency, Hyperthyroidism, Hyperthyroidism -- chemically induced, Thyroid Gland -- pathology, Endemic -- physiopathology, Mutation, Thyroid Gland -- physiopathology, Humans, Iodine -- therapeutic use, Goiter, Endemic, Iodine -- adverse effects, Iodine

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