The Hypoxic Placenta
Copyright policy )The Hypoxic Placenta
Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, hypertension, metabolic changes, oxidative stress, mitochondrial dysfunction, and endoplasmic reticular stress. Hypoxia induces similar outcomes in other organs such as the lungs, kidney, and gut. Comparing and contrasting the effects of hypoxia on placental functions and functions of lung, kidney, and gut can lead to novel hypotheses and investigations, furthering our understanding of the impact of hypoxia on these diverse yet similar organs. In this review, we compare and contrast hypoxic placental responses to those in the other organ and cell systems.
- University of Chile Chile
- Universidad Peruana Cayetano Heredia Peru
- University of Zurich Switzerland
- University of Santiago Chile Chile
Conference Paper, Oxygen Tension, Physiology, Hypoxia Inducible Factor 2alpha, Placenta, Blood Pressure, Protein Synthesis, Kidney, Placenta Disorder, Anoxia, Pregnancy, Hypoxia Inducible Factor 1alpha, Hypoxia, Lung, Pulmonary Hypertension, Altitude, General Medicine, Altitude Acclimatization, Placenta Circulation, 10081 Institute of Veterinary Physiology, Adaptation, Physiological, Mitochondria, Gastrointestinal System, Hypertension, Female, Public Health, Maternal Hypertension, https://purl.org/pe-repo/ocde/ford#3.03.05, Partial Pressure, Humans|Protein Expression, 610 Medicine & health, Protein Function, Vascular Remodeling, Fetal Hypoxia, 11554 Zurich Center for Integrative Human Physiology (ZIHP), Adaptation Physiological, Humans, Erythropoietin, Pulmonary Vascular Remodeling, Environmental and Occupational Health, 1314 Physiology, 2739 Public Health, Environmental and Occupational Health, Preeclampsia, Gastrointestinal Tract, Oxygen, Pregnancy Complications, Oxidative Stress, Placenta Function, 570 Life sciences; biology
Conference Paper, Oxygen Tension, Physiology, Hypoxia Inducible Factor 2alpha, Placenta, Blood Pressure, Protein Synthesis, Kidney, Placenta Disorder, Anoxia, Pregnancy, Hypoxia Inducible Factor 1alpha, Hypoxia, Lung, Pulmonary Hypertension, Altitude, General Medicine, Altitude Acclimatization, Placenta Circulation, 10081 Institute of Veterinary Physiology, Adaptation, Physiological, Mitochondria, Gastrointestinal System, Hypertension, Female, Public Health, Maternal Hypertension, https://purl.org/pe-repo/ocde/ford#3.03.05, Partial Pressure, Humans|Protein Expression, 610 Medicine & health, Protein Function, Vascular Remodeling, Fetal Hypoxia, 11554 Zurich Center for Integrative Human Physiology (ZIHP), Adaptation Physiological, Humans, Erythropoietin, Pulmonary Vascular Remodeling, Environmental and Occupational Health, 1314 Physiology, 2739 Public Health, Environmental and Occupational Health, Preeclampsia, Gastrointestinal Tract, Oxygen, Pregnancy Complications, Oxidative Stress, Placenta Function, 570 Life sciences; biology
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