Cactus Graphs for Genome Comparisons
Copyright policy )Cactus Graphs for Genome Comparisons
Abstract We introduce a data structure, analysis, and visualization scheme called a cactus graph for comparing sets of related genomes. In common with multi-break point graphs and A-Bruijn graphs, cactus graphs can represent duplications and general genomic rearrangements, but additionally, they naturally decompose the common substructures in a set of related genomes into a hierarchy of chains that can be visualized as two-dimensional multiple alignments and nets that can be visualized in circular genome plots. Supplementary Material is available at www.liebertonline.com/cmb .
- University of California, Santa Cruz United States
- University of Illinois at Urbana Champaign United States
- University of California, Davis United States
Genome, Base Sequence, Molecular Sequence Data, DNA, Genomics, Evolution, Molecular, Computer Graphics, Animals, Humans, Sequence Alignment, Algorithms
Genome, Base Sequence, Molecular Sequence Data, DNA, Genomics, Evolution, Molecular, Computer Graphics, Animals, Humans, Sequence Alignment, Algorithms
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