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Journal of Computational Biology
Article . 2009 . Peer-reviewed
License: Mary Ann Liebert TDM
Data sources: Crossref
https://dx.doi.org/10.48550/ar...
Article . 2008
License: arXiv Non-Exclusive Distribution
Data sources: Datacite
DBLP
Article . 2020
Data sources: DBLP
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Folding 3-Noncrossing RNA Pseudoknot Structures

Authors: Fenix W. D. Huang; Wade W. J. Peng; Christian M. Reidys;

Folding 3-Noncrossing RNA Pseudoknot Structures

Abstract

In this paper we present a selfcontained analysis and description of the novel {\it ab initio} folding algorithm {\sf cross}, which generates the minimum free energy (mfe), 3-noncrossing, $��$-canonical RNA structure. Here an RNA structure is 3-noncrossing if it does not contain more than three mutually crossing arcs and $��$-canonical, if each of its stacks has size greater or equal than $��$. Our notion of mfe-structure is based on a specific concept of pseudoknots and respective loop-based energy parameters. The algorithm decomposes into three parts: the first is the inductive construction of motifs and shadows, the second is the generation of the skeleta-trees rooted in irreducible shadows and the third is the saturation of skeleta via context dependent dynamic programming routines.

32pages, 27figures

Related Organizations
Keywords

RNA, Transfer, FOS: Mathematics, Mathematics - Combinatorics, Nucleic Acid Conformation, RNA, Combinatorics (math.CO), 05B30, Regulatory Sequences, Ribonucleic Acid, Algorithms

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Average
Average
Top 10%
Green
bronze