Identification of Three HIV-1 Unique (B/C) Recombinant Forms in Shaanxi, China
Copyright policy )Identification of Three HIV-1 Unique (B/C) Recombinant Forms in Shaanxi, China
HIV-1 intersubtype B/C recombinants were more commonplace reported in high-risk populations in Yunnan province, China. In this study, three unique (B/C) recombinant isolates (2015YL02, 2018YL07, and SN18015) were identified from patients infected with HIV-1 through sexual transmission in Shaanxi province. Phylogenetic and bootscan analyses showed that three recombinants comprised HIV-1 subtype B and subtype C. The recombinant structures revealed that the near full-length sequence of 2015YL02 shared an identical mosaic structure with XC2014EU20, which was isolated from Sichuan province. And two similar breakpoints were observed between 2018YL07 and CRF08_BC in pol gene. The arising B/C recombinant forms enrich evidence of the HIV-1 genetic diversity among sexually transmitted populations and suggest that continuously monitoring HIV-1 molecular epidemiology is needed in Shaanxi province.
- Chinese Center For Disease Control and Prevention China (People's Republic of)
Adult, Male, Recombination, Genetic, China, Genotype, Genetic Variation, HIV Infections, Genome, Viral, Sexually Transmitted Diseases, Viral, Sexual and Gender Minorities, HIV-1, Humans, Homosexuality, Male, Phylogeny, Aged
Adult, Male, Recombination, Genetic, China, Genotype, Genetic Variation, HIV Infections, Genome, Viral, Sexually Transmitted Diseases, Viral, Sexual and Gender Minorities, HIV-1, Humans, Homosexuality, Male, Phylogeny, Aged
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