Emergence of Circulating Recombinant Form 56_cpx in Pakistan

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2018 English Publisher:SAGE PublicationsJournal:AIDS Research and Human Retroviruses, volume 34, pages 1,002-1,004 (issn: 0889-2229, eissn: 1931-8405,

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Authors: Uroosa, Tariq; Azra, Parveen; Furqana, Akhtar; Faisal, Mahmood; Syed, Ali; Syed Hani, Abidi;

doi: 10.1089/aid.2018.0128

pmid: 29947245

Emergence of Circulating Recombinant Form 56_cpx in Pakistan

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Abstract

In Pakistan, HIV has converted from outbreak to concentrated epidemic and has also bridged into the low-risk population. The HIV epidemic in Pakistan mainly comprises subtype A. Here, we present the first case and genetic analysis of a circulating recombinant form 56_cpx in a Pakistani HIV-infected patient. Genetic analysis of the sequence indicated that Pakistani 56_cpx sequence had more drug resistance mutation than the other 56_cpx sequences available in the database.

Related Organizations

Nazarbayev University
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Memorial Hospital of South Bend
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Aga Khan University
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Shaukat Khanum Memorial Cancer Hospital and Research Center
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University of Oxford
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Keywords

Adult, Male, Recombination, Genetic, Genotype, Anti-HIV Agents, HIV Infections, Sequence Analysis, DNA, CD4 Lymphocyte Count, Drug Resistance, Multiple, Viral, DNA, Viral, Mutation, HIV-1, Humans, Pakistan, Phylogeny

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