A general form of a two-qubit system is obtained under the effect of Lorentz transformation. We investigate extensively some important classes in the context of quantum information. It is shown Lorentz transformation causes a decay of entanglement and consequently information loses. On the other hand, it generates entangled states between systems prepared initially in a separable states. The partial entangled states are more robust under Lorentz transformation than maximally entangled states. Therefore the rate of information lose is larger for maximum entangled states compared with that for partially entangled states.