Use of Spoligotype Analysis to Detect Laboratory Cross-Contamination
Copyright policy )Use of Spoligotype Analysis to Detect Laboratory Cross-Contamination
Spoligotype analysis identified false-positive isolates ofMycobacterium tuberculosiscaused by laboratory cross-contamination. Spoligotyping is faster, is less expensive than DNA fingerprinting, and can be used with a variety of media. Patients were reevaluated and had medications discontinued as a result of this investigation. Months of unnecessary patient follow-up and treatment were avoided.
- New York City Department of Health and Mental Hygiene United States
Cross Infection, Equipment Contamination, Humans, False Positive Reactions, Mycobacterium tuberculosis, Laboratories, Sensitivity and Specificity, Oligonucleotide Array Sequence Analysis, Specimen Handling
Cross Infection, Equipment Contamination, Humans, False Positive Reactions, Mycobacterium tuberculosis, Laboratories, Sensitivity and Specificity, Oligonucleotide Array Sequence Analysis, Specimen Handling
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