We model the hydrodynamic evolution of the plasma confined in a coronal loop, 30,000 km long, subject to the heating of nanoflares due to intermittent magnetic dissipative events in the MHD turbulence produced by loop footpoint motions. We use the time-dependent distribution of energy dissipation along the loop obtained from a hybrid shell model, occurring for a magnetic field of about 10 G in the corona; the relevant heating per unit volume along the loop is used in the Palermo-Harvard loop plasma hydrodynamic model. We describe the results, focusing on the effects produced by the most intense heat pulses, which lead to loop temperatures between 1 and 1.5 MK.