Molecular Characterization of theEscherichia coliFimH Adhesin

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2001 Australia English Publisher:Oxford University Press (OUP)Journal:The Journal of Infectious Diseases, volume 183, pages S28-S31 (issn: 0022-1899, eissn: 1537-6613,

Copyright policy )

Authors: Schembri, M. A.; Kjaergaard, K.; Sokurenko, E. V.; Klemm, P.;

doi: 10.1086/318847

pmid: 11171009

Molecular Characterization of theEscherichia coliFimH Adhesin

- Summary
- Subjects
- Metrics

Abstract

Bacterial adherence mediated by fimbriae is an essential prerequisite for colonization of the urinary tract. Uropathogenic Escherichia coli express a number of different adhesive organelles, including P, type 1, S, and F1C fimbriae [1]. Type 1, or mannose-sensitive, fimbriae are produced by >80% of all uropathogenic E. coli. It is now well established that the expression of type 1 fimbriae by E. coli is a virulence factor for pathogenesis of the urinary tract [2, 3]. A typical type 1 fimbriated bacterium has 200-500 peritrichously arranged fimbriae on its surface. A single type 1 fimbria

Country

Australia

Related Organizations

Keywords

Adhesins, Escherichia coli, Recombinant Fusion Proteins, Site, Type-1, Protein Structure, Tertiary, Fimbriae, Epitopes, Structure-Activity Relationship, Infectious Diseases, Mutagenesis, Escherichia coli, Humans, Fimbriae Proteins, Adhesins, Bacterial, 0605 Microbiology

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	44
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average