If the mean properties of clusters of galaxies are well described by the entropy-driven model, the distortion induced by the cluster population on the blackbody spectrum of the Cosmic Microwave Background radiation is proportional to the total amount of intracluster gas while temperature anisotropies are dominated by the contribution of clusters of about 10^{14} solar masses. This result depends marginally on cluster parameters and it can be used to estimate the number density of clusters with enough hot gas to produce a detectable Sunyaev-Zel'dovich effect. Comparing different cosmological models, the relation depends mainly on the density parameter Omega_m. If the number density of clusters could be estimated by a different method, then this dependence could be used to constrain Omega_m.

8 pages, 3 figures, submitted to ApJ Letters