We present results from the first three-dimensional numerical simulations of moderately supersonic cloud motion through a tenuous, magnetized medium. We show that the interaction of the cloud with a magnetic field perpendicular to its motion has a great dynamical impact on the development of instabilities at the cloud surface. Even for initially spherical clouds, magnetic field lines become trapped in surface deformations and undergo stretching. The consequent field amplification that occurs there and particularly its variation across the cloud face then dramatically enhance the growth rate of Rayleigh-Taylor unstable modes, hastening the cloud disruption.

4 pages, 2 figures, ApJ (Letter) in press. High resolution postscript figures available at http://www.msi.umn.edu/Projects/twj/mhd3d/