The centromere is a vital chromosomal structure that provides all living cells with the ability to faithfully partition their genetic material during mitotic and meiotic cell divisions. It functions by holding newly replicated sister chromatids together, allowing the attachment of spindle microtubules, and orchestrating the ordered movement of chromosomes to the daughter cells. The centromere has also been recognized as a “marshalling station” for a host of “passenger proteins” that appear transiently on the centromere during specific stages of the cell cycle (Earnshaw and Mackay 1994).