Developments concerning the period-luminosity (PL) relation for classical Cepheids are discussed with particular emphasis on the fact that Cepheids continue to provide the most homogeneous and reliable set of distances to many nearby galaxies. Observational programs relating to extragalactic Cepheids are also reviewed, and new distances and reddenings to individual galaxies are determined from these data using multiwavelength PL relations, based for the first time on self-consistent calibrating data sets. Three recent promising secondary extragalactic distance indicators (Tully-Fisher, planetary nebula luminosity functions, and surface-brightness fluctuations) tie their zero points to the Cepheid distance scale and give globally consistent values for the Hubble constant of about 80 km/sec/Mpc. Tying the Faber-Jackson relation and the supernova distance scales to the Leo and Virgo clusters yields similar results. Such a value for the Hubble constant is marginally inconsistent with new estimates of the ages of globular clusters, and it may prove to be a serious problem for standard cold-dark-matter models of the universe.